稳态闪光视诱发电位的临床应用

本文应用30Hz 闪光刺激,记录稳态闪光视诱发电位(Steady-state flash visual evoked poten-tials,FVEP),经离散富里叶转换(discrete Fourier transform,DFT),提取基波和二次谐波的幅值和相位作为记录波的特征值.应用此法,对46例(89只眼)正常人和78例(109只眼)眼病患者进行测定分析.结果表明,正常对照组的特征值在各年龄组间有显著性差异.病人组中,视神经疾病(35只眼),老年黄斑变性(25只眼)和已累及黄斑部的视网膜脱离组(9只眼)的异常视功能检出率分别为82.9%、92%和100%.28只白内障眼和12只玻璃体混浊眼,初步观察,术前稳态FVEP 正常或轻度降低者,术后视力可达0.4以上.本研究的主要意义在于评价图形 VEP 不能完成的患者的视功能。并集中反映与黄斑区视锥细胞相连的传入神经的电活动,计算机操作方便,能获取更有用的信息.眼科学报 1993;9:70-74。

THE CLINICAL USE OF STEADY-STATE FLASH VISUAL EVOKED POTETIALS

The authors applied 30Hz flash stimuli to record steady-state flash visual evoked poten- tials(FVEP)and extracted the amplitudes and phases of the first and second harmonics as the characteris- tic value by discrete Fourier transform(DFT).46 normal controls(89 eyes)and 78 patients(109 eyes)were detected and analysed by this method.The result showed that the characteristic values of the normal controls are significantly different in three age groups and showed the positive in 35 eyes with the optic never diseases(82.9%),25 eyes with age-related macular degeneration(92%),and 9 eyes with retinal detachment involved macular(100%).It indicates the method is a sensitive index to evaluate the macular visual function.After preliminary observation,the visual acuities of postoperation were found above 0.4 in cataracts(28 eyes)or opacities(12 eyes)if preoperative FVEP were normal and non-com- plicated,or less than 0.4 if preoperative FVEP were abnormal.This suggests the method is one of the ef- fective index to detect the postoperative vision of the media opacities.The advantages,disadvantages and the clinical applications were discussed.Eye Science 1993;9:70-74.