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Internalization of G-protein-coupled receptors: Implication in receptor function,physiology and diseases
Affiliation:1. Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK;2. Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, UK;3. Institute of Pharmacology and Toxicology and Bio-Imaging Center, University of Würzburg, Würzburg, Germany;4. Institute for Molecular Cell Biology, CMB-Center for Molecular Biomedicine, University Hospital Jena, Friedrich Schiller University Jena, Jena, Germany;1. Department of Physiology, Faculty of Medicine, Semmelweis University, Budapest, Hungary;2. MTA-SE Laboratory of Molecular Physiology, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary;1. Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA;2. Department of Biochemistry and Institute for Research in Immunology and Cancer, University of Montreal, Montreal, QC H3C 3J7, Canada;3. Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA;4. Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA;5. Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA;6. Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA;7. Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710, USA
Abstract:
Keywords:GPCR  cAMP  receptor internalization  TSH  LH  endosomal signaling  G protein-coupled receptor"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0050"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  (GPCR)  protein kinase A"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0060"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  (PKA)  cyclic adenosine monophosphate"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0070"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  (cAMP)  mitogen-activated protein kinase"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0080"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  (MAPK)  thyroid stimulating hormone"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0090"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  (TSH)  parathyroid hormone"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0100"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  (PTH)  protein kinase A"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0110"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  (PKA)  neurokinin"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0120"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  (NK)  clathrin-mediated endocytosis"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0130"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  (CME)  clathrin-coated pits"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0140"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  (CCPs)
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