Prognostic factors in esophageal cancer treated with curative intent |
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Affiliation: | 1. Bordeaux University of Medicine, Bordeaux, France;2. Department of Radiation Oncology, Haut-Lévêque Hospital, Pessac, France;3. INSERM UMR1035 University of Bordeaux, Bordeaux, France;4. Esophageal and Endocrine Surgery Unit, Visceral Surgery Department, Magellan Center, Bordeaux University Hospital, Pessac, France;5. Department of Hepatogastroenterology, Magellan Center, Bordeaux University Hospital, Pessac, France;6. INSERM, UMR1053 Bordeaux Research in Translational Oncology, BaRITOn, University of Bordeaux, Bordeaux, France |
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Abstract: | The overall prognosis of patients with esophageal cancer has improved in recent decades due to surgical and medical progress, but overall survival remains poor. Better patient selection and tailored treatment are needed. Different prognostic factors linked with the patient, tumoral characteristics and treatment with curative intent have been identified and are the purpose of this review. Tumor detection at an earlier stage, the advent of new molecules and therapeutic combinations, and the centralization of management in high-volume centers should help to improve the prognosis of esophageal cancer. Improved imaging techniques and a better prediction strategy should guide future treatments. |
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Keywords: | Chemoradiotherapy Chemotherapy Esophageal cancer Prognosis Surgery |
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