Actualité sur les mécanismes physiopathologiques des syndromes néphrotiques idiopathiques : lésions glomérulaires minimes et hyalinose segmentaire et focale |
| |
| Institution: | 1. Service de néphrologie transplantation et dialyse, centre hospitalier universitaire de Bordeaux, 33076 Bordeaux, France;2. Inserm U1026, université de Bordeaux, 33076 Bordeaux, France;1. Service de néphrologie, groupe hospitalier La Pitié-Salpêtrière, 75013 Paris, France;2. Service de chirurgie plastique, hôpital Tenon, 75015 Paris, France;1. Service de néphrologie, groupe hospitalier Pitié-Salpêtrière, 83, boulevard de l’Hôpital, 75013 Paris, France;2. Service de néphrologie et de dialyse, hôpital privé Claude-Galien, RAMSAY-Générale de Santé, 20, route de Boussy-Saint-Antoine, 91480 Quincy-sous-Sénart, France;1. Service de néphrologie, hôpital Bichat, 46, rue Henri-Huchard, 75877 Paris cedex 18, France;2. Université Paris Diderot, 5, rue Thomas-Mann, 75013 Paris, France;3. Inserm U1149, Département hospitalo-universitaire (DHU) Fibrosis-Inflammation-Remodeling (FIRE), 16, rue Henri Huchard, 75890 Paris cedex 18, France;1. Clinic of Nephrology, Clinical Center of Serbia, Belgrade, Serbia;2. Institute of Pathology, School of Medicine, University of Belgrade, Belgrade, Serbia;3. School of Medicine, University of Belgrade, Belgrade, Serbia |
| |
| Abstract: | Idiopathic nephrotic syndrome represents up to 30% of adult glomerulopathies. However, its prognosis according to remission, relapse and renal failure remains unchanged since the 80s and prediction remains difficult. Physiopathology of adult idiopathic nephrotic syndrome is complex and multifactorial, including immunologic and environmental factors and a putative permeability-circulating factor, still unknown. In this point of view, we propose to summarize actual knowledge about idiopathic minimal change disease and focal and segmental glomerulosclerosis physiopathology. |
| |
| Keywords: | Circulating permeability factor Focal and segmental glomerulosclerosis Idiopathic nephrotic syndrome Lymphocyte Minimal change disease Podocyte |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
