Fiber-based polarization-sensitive OCT for birefringence imaging of the anterior eye segment |
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Authors: | Masahiro Yamanari Satoru Tsuda Taiki Kokubun Yukihiro Shiga Kazuko Omodaka Yu Yokoyama Noriko Himori Morin Ryu Shiho Kunimatsu-Sanuki Hidetoshi Takahashi Kazuichi Maruyama Hiroshi Kunikata Toru Nakazawa |
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Affiliation: | 1.Engineering Department, Tomey Corporation, 2-11-33 Noritakeshinmachi, Nishi-ku, Nagoya, Aichi, 451-0051, Japan;2.Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan;3.Department of Ophthalmology, Iwaki Kyoritsu Hospital, 16 Kusehara, Uchigo Mimaya-machi, Iwaki, Fukushima 973-8555, Japan |
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Abstract: | We demonstrate a prototype system of polarization-sensitive optical coherence tomography (PS-OCT) designed for clinical studies of the anterior eye segment imaging. The system can measure Jones matrices of the sample with depth-multiplexing of two orthogonal incident polarizations and polarization-sensitive detection. An optical clock is generated using a quadrature modulator and a logical circuit to double the clock frequency. Systematic artifacts in measured Jones matrices are theoretically analyzed and numerically compensated using signals at the surface of the sample. Local retardation images of filtering blebs after trabeculectomy show improved visualization of subconjunctival tissue, sclera, and scar tissue of the bleb wall in the anterior eye segment.OCIS codes: (110.4500) Optical coherence tomography, (170.4500) Optical coherence tomography, (170.4470) Ophthalmology, (120.2130) Ellipsometry and polarimetry |
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