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Usefulness of 131I-SPECT/CT and 18F-FDG PET/CT in Evaluating Successful 131I and Retinoic Acid Combined Therapy in a Patient with Metastatic Struma Ovarii
Authors:Hyo Jung Seo  Young Hoon Ryu  Inki Lee  Hye Sook Min  Keon Wook Kang  Dong Soo Lee  Dae-hee Lee  June-Key Chung
Abstract:Metastatic struma ovarii is an extremely rare disease, and the treatment of choice has not been established. Here, we introduce the case of a 36-year-old female pregnant patient with metastatic struma ovarii. Initial treatment was an exploratory laparotomy to remove multiple peritoneal masses. After delivery, a total thyroidectomy was done for the further 131I-therapy. 131I-SPECT/CT and 18 F-FDG PET/CT showed multiple hepatic metastases and extensive peritoneal seeding nodules. Multiple 131I and retinoic acid combination therapies were performed, resulting in marked improvement. 131I-SPECT/CT and 18 F-FDG PET/CT were quite useful for evaluating the biologic characteristics of the metastases.
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