中文神经疾病临床对照试验数据库的建立

目的：建立中文神经疾病临床对照试验数据库。方法：分别采用计算机检索中国生物医学文献光盘数据库(CBMdisc)、中国循证医学图书馆(中文光盘版)临床对照研究数据库和人工检索与神经疾病相关的11种期刊和4本会议论文集，纳入已发表的神经疾病防治性研究的随机对照试验和有对照但未随机分组的临床对照研究，建立数据库并采用，Procite软件进行管理。结果：经计算机检索CBMdisc(1978年～2002年4月)和中国循证医学图书馆(中文光盘版)2002年1期，人工检索期刊11种，论文集4种。数据库共纳入与神经疾病有关的临床对照试验3641篇，其中随机对照试验828篇，占22．74％，临床对照研究(非随机但有对照)2813篇，占77．26％。结论：本数据库较为全面地收集了中国神经疾病领域已发表的防治性对照试验，为临床实践和卫生决策提供了该领域治疗方面中国当前的研究证据，也为Cochrane图书馆以及世界各国的临床对照试验数据库提供了资料，是对系统评价作者有帮助的资料来源

How to Establish a Chinese Clinical Controlled Trials Database of Neurology

Objective To establish a Chinese clinical controlled trials database of neurology. Methods We identified relevant studies by electronic searching of CBMdisc from 1978 to April 2002,and the Library of Evidence-Based Medicine (Chinese). We also searched manually 11 journals and 4 conference proceedingsrelevant to neurological diseases. The studies included in this database should becontrolled studies relevant to treatment on neurological disease, randomized or only controlled without randomization. Results 3 641 studies were included in this database. Conclusions The Chinese neurological trials database was established. This database will provide Chinese evidence on treatments of various neurological diseases. Studies in this database will also be included in the Cochrane Library to facilitate systematic reviewers.