| 碱性成纤维细胞生长因子对糖尿病烧伤难愈创面修复的影响 |
| |
| 引用本文： | 乐嘉芬,蒋荆华,吴娟. 碱性成纤维细胞生长因子对糖尿病烧伤难愈创面修复的影响[J]. 华中科技大学学报(医学版), 2000, 29(6): 545-546 |
| |
| 作者姓名： | 乐嘉芬 蒋荆华 吴娟 |
| |
| 作者单位： | 武汉市第三医院烧伤科，武汉 430060 |
| |
| 摘 要： | 观察碱性成纤维细胞生长因子（bFGF）对糖尿病患者烧伤难愈创面修复的影响。22例、27个糖尿病烧伤超过6周未愈合的创面，经清创后按150u/cm2创面应用外源性bFGF，每日1～2次，对照治疗前、后创面愈合情况。结果显示27个慢性难愈合创面在应用bFGF后，4周内全部愈合，总有效率达100%。提示bFGF能明显改善糖尿病烧伤难愈创面的修复环境，加速创面愈合。
|
| 关 键 词： | 糖尿病；烧伤；难愈创面；碱性成纤维细胞生长因子；修复 |
| 修稿时间： | 2000-08-22 |
Effect of Basic Fibroblast Growth Factor on the Healing of Cutaneous Burn Wounds in Diabetes Patients |
| |
| Le Jiafen,Jiang Jinghua,Wu Juan Burn Unit,Wuhan Third Hospital,Wuhan. Effect of Basic Fibroblast Growth Factor on the Healing of Cutaneous Burn Wounds in Diabetes Patients[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 2000, 29(6): 545-546 |
| |
| Authors: | Le Jiafen Jiang Jinghua Wu Juan Burn Unit Wuhan Third Hospital Wuhan |
| |
| Affiliation: | Le Jiafen,Jiang Jinghua,Wu Juan Burn Unit,Wuhan Third Hospital,Wuhan 430060 |
| |
| Abstract: | The effects of basic fibroblast growth factor (bFGF) on repairing cutaneous burn wounds in the diabetes patients were investigated. Twenty-seven wounds of 22 diabetes patients whose wound hadn't been re- paired over 6 weeks were locally treated with bFGF in a dosage of 150 U/cm2 for each wounds one or two times a day. The healing time of the wound was used to evaluate of treatment results. The results showed that all cu- taneous burn wounds cured within 4 weeks after treatment with the effective rate being 100%. The results in- dicated that bFGF can be used as a promoter to accelerate the healing of cutaneous burn wounds in the diabetes patients in clinical practice. |
| |
| Keywords: | diabetes mellitus burn cutaneous chronic wounds basic fibroblast growth factor repair |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
