Long-term application of lepirudin on chronic haemodialysis over 34 months after heparin-induced thrombocytopenia.

Sir, The development of heparin-induced thrombocytopenia (HIT) isa well-known complication of heparin therapy. Once the syndromeoccurs and is recognized, it is essential to immediately avoidany sources of heparin. If anti-coagulation is still required,other anti-coagulants should be considered such as lepirudin,argatroban, danaparoid or fondaparinux in the acute phase usuallyfollowed by