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食管双重染色对内镜检出特殊肠化型Barrett食管的诊断价值
引用本文:杨晓梅,赵婵娟,余月华,王岩,赵进,沈皓,呼圣娟.食管双重染色对内镜检出特殊肠化型Barrett食管的诊断价值[J].宁夏医学杂志,2010,32(2):141-142.
作者姓名:杨晓梅  赵婵娟  余月华  王岩  赵进  沈皓  呼圣娟
作者单位:宁夏银川市第一人民医院,宁夏,银川,750001
基金项目:银川市科技局资助项目 
摘    要:目的观察不同的染色方法对内镜检出Barrett食管(BE)的影响。方法对101例胃镜检查中怀疑BE食管的病人,随机分为单染组和双染组,在胃镜下分别用复方碘溶液(单染组)或复方碘溶液-美蓝(双染组)在食管下段进行染色,单染组在GEJ以上不着色的柱状上皮区即可疑BE上皮区,按四象限活检方法多点取活检送病理学检查;双染组未着色者按四象限活检方法在GEJ以上不染区取材,着色病例在蓝染区多点取材送组织病理学检查。结果单染组各种病理类型的BE(即柱状上皮)均不着色,正常食管黏膜(即鳞状上皮)呈棕色;双染组特殊肠化型BE着蓝色,责门型及胃底型BE仍然不着色。双染组肠化型BE的检出率为22.45%,而单染组肠化型BE的检出率为7.84%。双重染色中蓝染区诊断肠化型BE的敏感性84.62%,特异性94.74%,未着色区未检出肠化型BE。结论胃镜下用复方碘溶液-美蓝双重染色,采取“靶点活检”,提高了BE食管肠化型的检出率。

关 键 词:Barrett食管  内镜  复方碘溶液-美蓝染色

Diagnostic value of intestinal metaplasia in Barrett's esophagus with double staining under endoscope
YANG Xiao-mei,ZHAO Chan-juan,YU Yue-hua,et al..Diagnostic value of intestinal metaplasia in Barrett's esophagus with double staining under endoscope[J].Ningxia Medical Journal,2010,32(2):141-142.
Authors:YANG Xiao-mei  ZHAO Chan-juan  YU Yue-hua  
Institution:The First People's Hospital of Yinchuan/a>;Yinchuan 750001/a>;China
Abstract:Objective To investigate the diagnostic value of Barrett's esophagus using different staining technique under endoscope.Methods 101 patients with suspected Barrett's esophagus under endoscope were observed,among them 49 patients were stained with Lugol's solution(single staining group),while 51 patients were stained with Lugol's solution-methylene blue under endoscopy(double staining group),and then underwent biopsy.In single staining group biopsy specimens obtained from unstained areas according to 4 rando...
Keywords:Barrett's esophagus  Endoscopy  Lugol's solution-methylene blue staining  
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