P300在鉴别闭合性颅脑外伤患者真假昏迷的价值

目的：研究P300在鉴别闭合性颅脑外伤患者真假昏迷的价值。方法：将237例闭合性颅脑外伤患者根据其有否昏迷史分为有昏迷组，无昏迷组，假昏迷组及不详组，并对各组视觉（图像）刺激诱发的异常P300波潜伏期和波幅进行比较分析。结果：昏迷组与无昏迷组的P300潜伏期和波幅有非常显著的差异（P＜0．001）；昏迷组与假昏迷的P300潜伏期和波幅亦有非常显著的差异（P＜0．001）；但无昏迷组与假昏迷组间无明显差异（P＞0．05）；昏迷史不详组与无昏迷组间有显著差异（P＜0．05）。结论P300波的变化可作为判断闭合性颅脑外伤患者有无昏迷的一项客观指标，在外伤事故鉴定中有重要的参考价值。

The value of P300 in judging the true and false coma in patients with closed craniocerebral trauma

Objective To study the value of P 300 in judging the true and false coma in patients with closed craniocerebral trauma. Methods The latency and amplitude of abnormal P 300 evoked by visual (image) stimulation were compared and analyzed between 237 cases with closed craniocerebral trauma.which were divided into coma,non coma,false coma and noclear group.Results There was very remarkable diffe rence in the latency and amplitude of P 300 between coma group and non coma group ( P <0.001), there was very remarkable difference in the latency and amplitude of P 300 between true coma group and false coma group ( P <0.001), but there was no significant difference between false coma group and non coma group ( P >0 05). There was remarkable difference between the cases whose coma histories were unclear and non coma ( P <0.05).Conclusion The change of P 300 might be taken as an objective index in judging the true and false coma in patients with closed craniocerebral trauma. And it had an important reference value in judging the traumatic accident.