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注射用头孢地嗪钠在10%葡萄糖注射液中的稳定性
引用本文:张蓉晖,孙梁燕,杨文清,许永军. 注射用头孢地嗪钠在10%葡萄糖注射液中的稳定性[J]. 海峡药学, 2007, 19(11): 12-13
作者姓名:张蓉晖  孙梁燕  杨文清  许永军
作者单位:浙江宁波市医院中心李惠利医院,宁波,315040;浙江慈溪市人民医院,慈溪,315300
摘    要:目的观察注射用头孢地嗪钠与10%葡萄糖注射液配伍的稳定性。方法观察配伍液外观、pH值的变化,采用高效液相色谱法测定配伍液中头孢地嗪钠的含量。结果室温6h内头孢地嗪钠在10%葡萄糖注射液中含量、外观、pH值基本不变。结论室温6h内注射用头孢地嗪钠在10%茑萄糖注射液中的是稳定的。

关 键 词:头孢地嗪钠  10  葡萄糖注射液  稳定性  高效液相色谱法
文章编号:1006-3765(2007)011-0012-02

Stability of cefodizime sodium for injection in 10% glucose injection
ZHANG Rong-hui,SUN Liang-yan,YANG Wen-qing,XU Yong-jun. Stability of cefodizime sodium for injection in 10% glucose injection[J]. Strait Pharmaceutical Journal, 2007, 19(11): 12-13
Authors:ZHANG Rong-hui  SUN Liang-yan  YANG Wen-qing  XU Yong-jun
Abstract:OBJECTIVE To study the stability of cefodizime sodium for injection in 10% glucose injection.METHODS To observe the appearance and to determinae pH value of the mixed fluid,the content of cefodizime sodium could be determined by HPLC.RESULTS There was no evident changes in appearance,pH value and the content of cefodizime sodium withine 6h at room temperature in 10% glucose injection.CONCLUSION Cefodizime sodium for injection was shown to be stable in 10% glucose injection within 6h.
Keywords:cefodizime sodium  10%glocose injection  stability  HPLC
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