122例急性戊型肝炎重叠感染患者的肝功能及临床特点分析

目的 比较分析单纯急性戊型肝炎与重叠感染患者的肝功能指标和临床特点.方法 以40例单纯急性戊型肝炎为对照,回顾性分析了122例重叠感染戊型肝炎患者的肝功能指标、临床资料.结果 单纯戊肝组、甲戊重叠感染组、乙戊重叠感染组,三组之间ALT、AST、TBIL、DBIL差异均无统计学意义(P0.05),急性戊肝组与乙戊重叠感染组,甲戊重叠感染组与乙戊重叠感染组的白蛋白、球蛋白有统计学差异(P<0.01);甲戊重叠感染、乙戊重叠感染与单纯戊肝相比较临床合并症多、并发症重.结论 戊型肝炎重叠感染,特别是乙戊重叠感染患者,要加强临床监测,提高早期预防并发症的意识,以降低病死率.

Analysis of liver function index and clinical characters in 122 patients with acute hepatitis E virus coinfection with other hepatitis virus

Objective To eompare the liver function index and clinical characters in 122 patients with acute hepatitis E virus overlapping with other infection. Methods The liver function index and clinical characters of 122 patients with acute hepatitis E virus overlapping infection and 40 patients with acute hepatitis E were retrospectively analyzed. Results No significant differences of ALT, AST, TBIL, DBIL were found between acute hepatitis E groups and overlapping infection hepatitis A or hepatitis B(P 0.05).However, there were significant differences of Albumin (ALB) and Globulin (GLO) were found between acute hepatitis E groups and overlapping infection hepatitis B(P < 0.01). In acute hepatitis E overlapping infected hepatitis B or hepatitis A patients, more and severe complications were also observed. Conclusion The patients with acute Hepatitis E virus, especially Hepatitis E virus overlapping infection, need to pay more clinical monitor, prevent complication early and lower death rates.