| FAK 与肿瘤关系的研究进展 |
| |
| 引用本文： | 李玲妹(综述),曹文枫(审校). FAK 与肿瘤关系的研究进展[J]. 中国肿瘤临床, 2015, 42(2): 116-119. DOI: 10.3969/j.issn.1000-8179.20141430 |
| |
| 作者姓名： | 李玲妹(综述) 曹文枫(审校) |
| |
| 作者单位： | 作者单位:天津医科大学肿瘤医院病理科,国家肿瘤临床医学研究中心,天津市肿瘤防治重点实验室(天津市300060) |
| |
| 摘 要： | 着斑激酶（focal adhesion kinase ，FAK ）是一种细胞质内的蛋白酪氨酸激酶（protein tyrosine kinase ，PTK ），因其与细胞粘附功能密切相关而得名。近年来，人们对FAK 的了解逐渐深入，国内外大量研究表明FAK 在多种肿瘤组织中表达增高，并与肿瘤的多个过程有着密切的关系。FAK 已经成为新的肿瘤治疗靶点之一，为肿瘤的治疗带来新的方法和希望。
|
| 关 键 词： | 粘着斑激酶 肿瘤 转移 凋亡 |
| 收稿时间： | 2014-08-22 |
Research progress on the relationship between FAK and cancer |
| |
| Lingmei LI,Wenfeng CAO. Research progress on the relationship between FAK and cancer[J]. Chinese Journal of Clinical Oncology, 2015, 42(2): 116-119. DOI: 10.3969/j.issn.1000-8179.20141430 |
| |
| Authors: | Lingmei LI Wenfeng CAO |
| |
| Affiliation: | Department of Pathology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China |
| |
| Abstract: | Focal adhesion kinase (FAK), a type of protein tyrosine kinase in the cytoplasm, is highly expressed in many types of malignant tumors. FAK is named as such because of its close relationship with the cell adhesion function. Recent studies show that FAK is expressed in many tumor cells and has a definite relationship with cancer progress, metastasis, and prognosis. Accordingly, FAK has become one of the new tumor therapeutic targets that will bring new methods for tumor therapy. |
| |
| Keywords: | focal adhesion kinase cancer metastasis apoptosis |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《中国肿瘤临床》浏览原始摘要信息 |
|
点击此处可从《中国肿瘤临床》下载免费的PDF全文 |
|
