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Patient acceptability of larval therapy for leg ulcer treatment: a randomised survey to inform the sample size calculation of a randomised trial
Authors:ES Petherick  S O'Meara  K Spilsbury  CP Iglesias  EA Nelson  DJ Torgerson
Institution:(1) Centre for Evidence Based Nursing, Department of Health Sciences, University of York, Heslington, YO10 5DD, UK;(2) Department of Health Sciences, University of York, Heslington, YO10 5DD, UK;(3) York Trials Unit, Department of Health Sciences, University of York, Heslington, YO10 5DD, UK;(4) School of Healthcare, University of Leeds, Leeds, LS2 9UT, UK
Abstract:

Background  

A trial was commissioned to evaluate the effectiveness of larval therapy to debride and heal sloughy and necrotic venous leg ulcers. Larval therapy in the trial was to be delivered in either loose or bagged form. Researchers were concerned that resistance to larval therapy may threaten the feasibility of the trial. Additionally there was concern that the use of larval therapy may require a larger effect size in time to healing than originally proposed by the investigators.
Keywords:
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