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呼吸科ICU病房院内肺部真菌感染51例临床分析
引用本文:李春. 呼吸科ICU病房院内肺部真菌感染51例临床分析[J]. 甘肃医药, 2009, 28(5): 330-332
作者姓名:李春
作者单位:兰州市第二人民医院呼吸内科,甘肃兰州730046
摘    要:目的:了解近年来呼吸科重症监护病房(RICU)院内肺部真菌感染的发病情况、相关因素、菌株分析及治疗现状。方法:对2003年1月~2008年12月我院RICU诊断的51例院内肺部真菌感染患者的临床资料进行回顾性分析。结果:近六年RICU共诊断51例院内肺部真菌感染患者,均为临床诊断,其发病率显著高于同时期普通病房的发病率(11.78%比1.75%,P〈0.01)。COPD和细菌性肺炎是最常见的呼吸系统基础疾病分别占33.3%和35.3%;43例(84.3%)患者具有肺部真菌感染的高危因素。与普通病房相比,RICU患者的曲霉菌感染所占比例更高(9.8%),但二者元显著差异(P〉0.05)。抗真菌治疗有效率为82.4%,氟康唑为最常见的抗真菌药物。与普通病房相比,RICU患者的死亡率升高为17.6%,但二者无显著差异(P〉0.05)。结论:RICU患者院内肺部真菌感染的发病率明显高于普通病房,因预后相对较差,应早期采用有效的干预措施。

关 键 词:肺炎  真菌感染  医院感染  重症监护病房

Clinical analysis of 51 cases with nosocomial pulmonary fungal infection in respiratory intensive care unit
LI Chun Respiratory. Clinical analysis of 51 cases with nosocomial pulmonary fungal infection in respiratory intensive care unit[J]. , 2009, 28(5): 330-332
Authors:LI Chun Respiratory
Affiliation:LI Chun Respiratory department of the second people's hospital of Lanzhou city,Gansu province,Lanzhou 730046,China
Abstract:Objective:To analyze the morbility,risk factors,etiology,treatment and outcome of nosocomial pulmonary fungal infections in respiratory intensive care unit(RICU).Methods: 51 patients with nosocomial pulmonary fungal infections in RICU between Jan 2003 and Dec 2008 were retrospectively analyzed. Results:All of 51 cases were clinically diagnosed as probable nosocomial pulmonary fungal infections,with the morbidity of 11.78% significantly higher than general wards(1.75%,P<0.01).COPD and bacterial pneumonia wer...
Keywords:Pneumonia  Fungal infections  Nosocomial infections  Intensive care unit  
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