呼吸科ICU病房院内肺部真菌感染51例临床分析 |
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引用本文: | 李春.呼吸科ICU病房院内肺部真菌感染51例临床分析[J].甘肃医药,2009,28(5):330-332. |
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作者姓名: | 李春 |
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作者单位: | 兰州市第二人民医院呼吸内科,甘肃兰州730046 |
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摘 要: | 目的:了解近年来呼吸科重症监护病房(RICU)院内肺部真菌感染的发病情况、相关因素、菌株分析及治疗现状。方法:对2003年1月~2008年12月我院RICU诊断的51例院内肺部真菌感染患者的临床资料进行回顾性分析。结果:近六年RICU共诊断51例院内肺部真菌感染患者,均为临床诊断,其发病率显著高于同时期普通病房的发病率(11.78%比1.75%,P〈0.01)。COPD和细菌性肺炎是最常见的呼吸系统基础疾病分别占33.3%和35.3%;43例(84.3%)患者具有肺部真菌感染的高危因素。与普通病房相比,RICU患者的曲霉菌感染所占比例更高(9.8%),但二者元显著差异(P〉0.05)。抗真菌治疗有效率为82.4%,氟康唑为最常见的抗真菌药物。与普通病房相比,RICU患者的死亡率升高为17.6%,但二者无显著差异(P〉0.05)。结论:RICU患者院内肺部真菌感染的发病率明显高于普通病房,因预后相对较差,应早期采用有效的干预措施。
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关 键 词: | 肺炎 真菌感染 医院感染 重症监护病房 |
Clinical analysis of 51 cases with nosocomial pulmonary fungal infection in respiratory intensive care unit |
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Authors: | LI Chun Respiratory |
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Institution: | LI Chun Respiratory department of the second people's hospital of Lanzhou city,Gansu province,Lanzhou 730046,China |
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Abstract: | Objective:To analyze the morbility,risk factors,etiology,treatment and outcome of nosocomial pulmonary fungal infections in respiratory intensive care unit(RICU).Methods: 51 patients with nosocomial pulmonary fungal infections in RICU between Jan 2003 and Dec 2008 were retrospectively analyzed. Results:All of 51 cases were clinically diagnosed as probable nosocomial pulmonary fungal infections,with the morbidity of 11.78% significantly higher than general wards(1.75%,P<0.01).COPD and bacterial pneumonia wer... |
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Keywords: | Pneumonia Fungal infections Nosocomial infections Intensive care unit |
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