应用光学相干断层成像术测量正常人黄斑视网膜厚度的初步研究

目的：应用光学相干断层成像术（ｏｐｔｉｃａｌ ｃｏｈｅｒｅｎｃｅ ｔｏｍｏｇｒａｐｈｙ，ＯＣＴ）测量我国正常人贡斑视网膜神经上皮层（ｒｅｔｉｎａｌ ｎｅｕｒｏｓｅｎｓｏｒｙ ｌａｙｅｒ）和色素上皮层（ｒｅｔｉｎａｌ ｐｉｇｍｅｔ ｅｐｉｔｈｅｌｉｕｍ，ＲＰＥ）与脉络膜毛细血管层的厚度。方法：用ＯＣＴ对６０例（１２０眼）正常人进行经黄斑中央小凹水平和垂直扫描，扫描长度４ｍｍ，测量并计算黄斑中央小凹；

Quantitative Measurement of Macular Thickness in Normal Subjects by Optical Coherence Tomography

OBJECTIVE: To measure the thickness of retinal neurosensory layer, retinal pigment epithelium (RPE) and choriocapillaris in normal subjects by optical coherence tomography (OCT). METHODS: Sixty normal subjects (120 eyes) were examined by OCT with 4 mm scanning length horizontally and vertically through foveola. The mean thickness of retinal neurosensory layer, RPE and choriocapillaris thickness in foveola, 175 microns and 750 microns to foveola, were calculated and compared. RESULTS: The mean thickness of retinal neurosensory layer is 146.34 +/- 8.58 microns in foveola; 155.58 +/- 10.20 microns in 175 microns to foveola and 252.98 +/- 14.07 microns in 750 microns to foveola. The mean thickness of RPE and choriocapillaris is 106.26 +/- 10.58 microns in foveola; 104.98 +/- 7.24 microns in 175 microns to foveola and 106.84 +/- 9.95 microns in 750 microns to foveola. The results show that there are no significant in mean thickness of retinal neurosensory layer in 175 microns to foveola in statistics, but there are differences in 750 microns to foveola between nasal and temporal or superior, inferior and nasal, temporal. The differences in mean RPE and choriocapillaris thickness of all sites are not significant. Correlative analysis showed that there is no correlation between retinal neurosensory layer, RPE and choriocapillaris thickness and age. CONCLUSION: OCT can accurately measure the thickness of retina in normal eyes and provide a subjective and Quantitative method to diagnose macular diseases.