Overexpression of the BCL2 gene in a Sertoli-Leydig cell tumor of the ovary: a pathologic and cytogenetic study |
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| Authors: | Truss Lisa Dobin Sheila M Rao Arundati Donner Ludvik R |
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| Institution: | Scott, Sherwood and Brindley Foundation, The Texas A and M University System Health Science Center, College of Medicine, 2401 South 31st Street, Temple, TX 76508, USA. |
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| Abstract: | A case of virilizing ovarian Sertoli-Leydig cell tumor overexpressing the BCL2 gene and including a novel clonal chromosomal rearrangement of chromosome 18, der(5)t(5;18)(p13;q12),+6,+12, der(18)r(5;18)(p15.3p13;p11.3q12) is described. Further studies of these rare tumors are necessary to ascertain the significance of the findings. |
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