国产异丙肌苷对小鼠免疫功能影响的研究

 本实验研究了国产异丙肌苷对小鼠几个免疫学指标的影响。结果表明,异丙肌苷在体内外均能有意义地增加淋巴细胞转化,但单独对小鼠淋巴细胞无明显作用。异丙肌苷还能显著增强巨噬细胞的功能及血清溶菌酶含量。此外亦能使抗体反应明显增加。因而提示异丙肌苷对小鼠免疲功能具有促进作用。本文还讨论了其可能的作用机理。

EFFECTS OF ISOPRINOSINE ON IMMUNE FUNCTIONS OF THE MICE

The effects of isoprinosine on the immunofunctions of the mice were investigated.The results showed that isoprinosine could enhance the proliferation of theconcanavalin A-induced lymphocyte both in vivo and in vitro of the mice. Butthere was no effect on lymphcyte by single drug treatment. Compared with thecontrol groups. isoprinosine also could enhance the furction of macrophages andaugment serum lysozyme concentration significantly, it could enhance the immu-noresponse to the SRBC too. These suggest that isoprinosine is a promising immu-noregulator which can enhance the immune functions of the mice, but the effecton immune functions for human being should be further studied.