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Endoscopic mucosal resection of large hyperplastic polyps in 3 patients with Barrett's esophagus
引用本文:De Ceglie A,Lapertosa G,Blanchi S,Di Muzio M,Picasso M,Filiberti R,Scotto F,Conio M. Endoscopic mucosal resection of large hyperplastic polyps in 3 patients with Barrett's esophagus[J]. World journal of gastroenterology : WJG, 2006, 12(35): 5699-5704. DOI: 10.3748/wjg.v12.i35.5699
作者姓名:De Ceglie A  Lapertosa G  Blanchi S  Di Muzio M  Picasso M  Filiberti R  Scotto F  Conio M
摘    要:

关 键 词:内窥镜  息肉  食管疾病  治疗
收稿时间:2006-02-09

Endoscopic mucosal resection of large hyperplastic polyps in 3 patients with Barrett's esophagus
De Ceglie Antonella,Lapertosa Gabriella,Blanchi Sabrina,Di Muzio Marcello,Picasso Massimo,Filiberti Rosangela,Scotto Francesco,Conio Massimo. Endoscopic mucosal resection of large hyperplastic polyps in 3 patients with Barrett's esophagus[J]. World journal of gastroenterology : WJG, 2006, 12(35): 5699-5704. DOI: 10.3748/wjg.v12.i35.5699
Authors:De Ceglie Antonella  Lapertosa Gabriella  Blanchi Sabrina  Di Muzio Marcello  Picasso Massimo  Filiberti Rosangela  Scotto Francesco  Conio Massimo
Affiliation:1. Department of Gastroenterology, National Cancer Institute, Bari, Italy
2. Department of Surgical and Morphological Sciences, Division of Pathology, University of Genova, Genova,Italy
3. Department of Gastroenterology, General Hospital, Sanremo, Italy
4. Department of Pathology, General Hospital, Sanremo, Italy
5. Division of Enviromental Epidemiology and Biostatistics, National Cancer Research Institute, Genova, Italy
Abstract:AIM: To report the endoscopic treatment of large hyperplastic polyps of the esophagus and esophago-gastric junction (EGJ) associated with Barrett's esophagus (BE) with low-grade dysplasia (LGD), by endoscopic mucosal resection (EMR). METHODS: Cap fitted EMR (EMR-C) was performed in 3 patients with hyperplastic-inflammatory polyps (HIPs) and BE. RESULTS: The polyps were successfully removed in the 3 patients. In two patients, with short segment BE (SSBE) (<= 3 cm), the metaplastic tissue was completely excised. A 2 cm circumferential EMR was performed in one patient with a polyp involving the whole EGJ. A simultaneous EMR-C of a BE-associated polypoid dysplastic lesion measuring 1 cm multiply 10 cm, was also carried out. In the two patients, histologic assessment detected LGD in BE. No complications occurred. Complete neosquamous re-epithelialization occurred in the two patients with SSBE. An esophageal recurrence occurred in the remaining one and was successfully retreated by EMR. CONCLUSION: EMR-C appears to be a safe and effective method for treating benign esophageal mucosal lesions, allowing also the complete removal of SSBE.
Keywords:Hyperplastic polyps  Endoscopic mucosal resection  Barrett's esophagus
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