| 大鼠运动力竭后生理生化因素对PWN粘弹性影响的实验研究 |
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| 引用本文： | 秦廷武,杨瑞芳,蒋稼欢,蔡绍皙,吴云鹏.大鼠运动力竭后生理生化因素对PWN粘弹性影响的实验研究[J].中国血液流变学杂志,1998(1). |
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| 作者姓名： | 秦廷武 杨瑞芳 蒋稼欢 蔡绍皙 吴云鹏 |
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| 作者单位： | 重庆大学生物工程研究院!重庆630044 |
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| 基金项目： | 国家自然科学基金资助项目（编号：39470282） |
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| 摘 要： | 本文利用微吸管实验方法，研究了ｐＨ值，乳酸，肾上腺素和能量物质对大鼠运动力竭前后多形核中性粒细胞（Ｐｏｌｙｍｏｒｐｈｏｎｃｌｅａｒ ｎｅｕｔｒｏｐｈｉｌｓ，ＰＭＮｓ）粘弹性的影响。结果发现随着乳酸浓度、肾上腺素浓度的增加，大鼠ＰＭＮ粘弹性参数发生不同程度的增加，变形性发生相应的变化；随着ｐＨ值从 ７．４下降到６．４，ＰＭＮ粘弹性参数逐渐增大；但是ＰＭＮ粘弹性不受葡萄糖和ＡＴＰ浓度的影响。
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| 关 键 词： | 力竭运动 多形核中性粒细胞 粘弹性 大鼠 |
EFFECTS OF PHYSIOCHEMICAL FACTORS ON VISCOELASTIC PROPERTIES OF RAT PMNS BEFORE AND AFTER EXHAUSTING EXERCISE |
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| Qin Tingwu et al.EFFECTS OF PHYSIOCHEMICAL FACTORS ON VISCOELASTIC PROPERTIES OF RAT PMNS BEFORE AND AFTER EXHAUSTING EXERCISE[J].Chinese Journal of Hemorheology,1998(1). |
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| Authors: | Qin Tingwu |
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| Abstract: | IV VITRO approaches, this investigation was perfomed to study the effects of physiochemical factors on rheology ear OMNs before and after exhausting exercise with the micropipette aspirating experiment method. Extracellular adrenaline and lactic acid concentration had significantly influence on the viscoelastic coefficients of rat PMNs. Variations in pH over the range of 6. 4-7. 4 significantly affected the viscoelastic coefficients. However, in suspension media with glucose and ATP, the neutrophils did not exhibit significant changes in K1,K2and u. |
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| Keywords: | Exhausting exercise Polymorphonuclear neutrophils Viscoelastic properties Rat |
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