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路易体痴呆的诊断
引用本文:刘宪霜,贾建军,王鲁宁,许丹. 路易体痴呆的诊断[J]. 中风与神经疾病杂志, 2003, 20(3): 213-215
作者姓名:刘宪霜  贾建军  王鲁宁  许丹
作者单位:中国人民解放军总医院老年神经科,北京,100853
摘    要:目的 探讨路易体痴呆(dementia with Lewy body,DLB)的早期诊断。方法 根据病理确诊的1例DLB患者和3例临床诊断DLB患者的症状、体征和影像学变化,分析DLB的临床特征。结果 4例息者都有以下特点:(1)波动性进行性痴呆;(2)生动的视幻觉;(3)锥体外系症状;(4)对神经安定剂敏感。结论 根据以上特点,生前诊断DLB是可能的,对疑诊DLB的患者应慎用神经安定剂和抗胆碱能类药物。

关 键 词:路易体痴呆 早期诊断 临床特征 影像学检查 认知功能
文章编号:1003-2754(2003)03-0213-03
修稿时间:2002-11-12

The diagnosis of dementia with Lewy body
LIU Xian shuang,JIA Jian jun,WANG Lu ning,et al.. The diagnosis of dementia with Lewy body[J]. Journal of Apoplexy and Nervous Diseases, 2003, 20(3): 213-215
Authors:LIU Xian shuang  JIA Jian jun  WANG Lu ning  et al.
Abstract:Objective To investigate the early characteristic diagnosis of dementia with Lewy body(DLB). Methods Clinical symptoms and signs of one patient diagnosed by pathologic autopsy and three patients by clinical symptoms were studied through retrospective analysis. Results Clinical characters of four patients were as followed:(1)fluctuating progressive dementia;(2)vivid visual hallusination;(3)extrapyramidal signs;(4)sensitive to neuroleptic drugs. Conclusion It is possible to make a positive clinical diagnosis by the key features of DLB. Patients suspected DLB should avoid using neuroleptic drugs and anticholinic drugs.
Keywords:Dementia with Lewy body  Diagnosis  Clinical features
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