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细胞密度与表观弥散系数的相关性探讨
引用本文:赵继红,ゥットハムス玲子,丁军,蒋世旭,杨海山,早川和重. 细胞密度与表观弥散系数的相关性探讨[J]. 中国实验诊断学, 2006, 10(4): 379-382
作者姓名:赵继红  ゥットハムス玲子  丁军  蒋世旭  杨海山  早川和重
作者单位:1. 日本北里大学医学部,放射线科;吉林大学中日联谊医院,放射线科
2. 日本北里大学医学部,放射线科
3. 吉林大学中日联谊医院,放射线科
基金项目:长春市社会发展科技计划资助项目(长科技合2004057)
摘    要:目的研究乳腺磁共振成像(Magnetic resonance imaging,MRI)弥散加权像(diffiusion-weighted image,DWI)中表观弥散系数(apparent diffusion coefficient,ADC)的影响因素。方法对照病理分析32例乳腺疾病患者的42个ADC值异常的感兴趣区,分析ADC的相关影响因素。结果乳腺问质成分百分比与ADC值呈正比趋势,随间质百分比的增加ADC值增加。肿瘤组织内出血、坏死及间质成分中纤维细胞排列的疏密对ADC有明显影响。结论细胞密度是ADC值的主要影响因素,与ADC值密切相关。

关 键 词:磁共振成像  乳腺疾病  表观弥散系数  间质百分比
文章编号:1007-4287(2006)04-0379-04
收稿时间:2005-04-01
修稿时间:2005-04-01

The correlative study of the breast cells density and apparent diffusion coefficient
ZHAO Ji-hong, Woodhams Reiko, DING Jun,et al.. The correlative study of the breast cells density and apparent diffusion coefficient[J]. Chinese Journal of Laboratory Diagnosis, 2006, 10(4): 379-382
Authors:ZHAO Ji-hong   Woodhams Reiko   DING Jun  et al.
Affiliation:ZHAO Ji-hong, Woodhams Reiko, DING Jun, et al.
Abstract:Objective To investigate the influencing factors on Apparent diffusion coefficient(ADC) of diffusion-weighted image(DWI) in breast magnetic resonance imaging(MRI).Methods Compared to pathological findings,42 regions of interest(ROI) with abnormal ADC value in 32 DWI images of breast disease were analyzed to investigate the correlative factor on ADC.Results ADC increases in direct proportion to the percentage increment of breast stroma.Hemorrhage,necrosis in tumor tissue and the density of fibrous cell in stroma have significant effect on ADC.Conclusion Density of breast cells is the primary influencing factor on ADC,correlating closely with ADC value.
Keywords:M ogndic resonance imaging   breast disease   apparent diffusion coefficient  the percentage of stroma
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