| 柴桂解表颗粒质量标准的研究 |
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| 引用本文： | 张沂,蔡清宇,唐慧慧,郭宇姝.柴桂解表颗粒质量标准的研究[J].解放军药学学报,2008,24(5):395-397. |
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| 作者姓名： | 张沂 蔡清宇 唐慧慧 郭宇姝 |
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| 作者单位： | 海军总医院,药剂科,北京,100037;海军总医院,药剂科,北京,100037;海军总医院,药剂科,北京,100037;海军总医院,药剂科,北京,100037 |
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| 摘 要： | 目的建立柴桂解表颗粒的质量标准。方法采用TLC法对柴桂解表颗粒中的桂枝、黄芩、麻黄、甘草进行定性鉴别，用HPLC法测定该制剂中芍药苷的含量。结果薄层色谱法可鉴别出该制剂中的桂枝、黄芩、麻黄、甘草。芍药苷在0.063-1.260μg范围内线性关系良好，r=0.9999，样品的平均加样回收率为97.30％，RSD为1.84％，（n=6）。结论薄层色谱法斑点显色清晰，专属性强，高效液相色谱法操作简便、准确、重复性好，可用于柴桂解表颗粒的质量控制。
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| 关 键 词： | 柴桂解表颗粒 TLC HPLC 芍药苷 |
Study on The Quality Standard of Chaiguijiebiao Granule |
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| ZHANG Yi,CAI Qing-Yu,TA Hui-Hui,GUO Yu-Shu.Study on The Quality Standard of Chaiguijiebiao Granule[J].Pharmaceutical Journal of Chinese People's Liberation Army,2008,24(5):395-397. |
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| Authors: | ZHANG Yi CAI Qing-Yu TA Hui-Hui GUO Yu-Shu |
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| Institution: | (Department of Pharmacy, Navy General Hospital, Beijing 100037 China) |
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| Abstract: | Aim To establish a quality standard for Chaiguijiebiao Granule. Methods Ramulus cinnamomi, radix scutellariae,herba ephedrae,radix et rhizome glycyrrhizae were identified by TLC,and the contents of paeoniflorin in Chaiguijiebiao Granule were determined by HPLC. Results TLC can clearly identify the ramulus cinnamomi ,radix scutellariae,herba ephedrae and radix et rhizome glycyrrhizae of this Chinese herbal preparation. The linear range of paeoniflorin was 0.063- 1.260μg,（r=0.9999）, with an average recovery rate of 97.30%, RSD =1.84% ,（n =6）. Conclusion In TLC ,the spots are clear and specific enough to identify the herbal medicine in Chaiguijiebiao Granule. The method is simple and accurate with good reproducibility in HPLC. It can be used for quality control of Chaiguijiebiao Granule. |
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| Keywords: | TLC HPLC |
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