耳声发射在新生儿重症监护病房的应用研究

目的 探讨应用畸变产物耳声发射（distortion product otoacoustic emiSSions，DPOAE）技术在新生儿重症监护室（neonatal intesive care unit，NICU）进行听力筛查的敏感性和假阴性。方法 应用GSI70全自动畸变产物耳声发射仪对本院新生儿重症监护病房的116名婴儿在住院期间进行听力筛查，与听性脑干反应（auditory brainstem response，ABR）测试结果进行对照。结果 在116例（232耳）患儿中，DPOAE和ABR测试结果的共同阳性率分别为42．19％，共同阴性率分别为93．45％，DPOAE测试中的假阴性率为57．81％，假阳性率为6．55％。结论 在NICU中，应用DPOAE进行听力筛查具有较高的假阴性，会造成耳蜗功能正常的中枢性听损伤漏诊，ABR测试为比较可靠的新生儿听力筛查方法，用于NICU婴儿进行初筛更具有特殊意义。

Otoacoustic Emissions in Neonatal Intensive Care Unit for Hearing Screening

Objective To evaluate the effectiveness of distortion product otoacoustic emissions for hearingscreening in neonatal intensive care unit . Methods 116 infants (232 ears) were screened by DPOAE with GSI70Automatic OAE . The outcome of DPOAE screening was compared with that of auditory brainstem response(ABR)test . Results Of 116(232ears) newborns , the co-positivity and co-negativity of DPOAE and ABR were42.19%(27/64ears) and 93.45%(157/168. The false negativity and false positivity of DPOAE were57.81% (37 /64ears)and6.55%(11/168ears). Conclusion In NICU , DPOAE screening made a high false negativity that may lead thecentral hearing loss missed , while ABR test has an important significance in first hearing screening forinfants of NICU as a reliable method.