不同性别高尿酸血症患者的影响因素调查

目的 比较不同性别高尿酸血症患者的临床特征和影响因素,为更好地控制和预防高尿酸血症的发生、发展提供依据.方法 以2016年1月1日至6月1日保定市两家体检中心5 783例体检者为调查对象,对其进行体格检查、实验室检查及问卷调查.分析其中高尿酸血症者的临床特征,并分析其影响因素.结果 男、女高尿酸血症患者在肥胖、血压、血糖、血脂、肝功、肾功、贫血、血流变检查、甲状腺彩超及颈椎侧位片10个方面的临床特征比较,差异有统计学意义(P＜0.05).问卷调查显示,男、女高尿酸血症患者在年龄、学历、婚姻状况、工作状况、睡眠情况、吸烟、饮酒7个因素上比较,差异有统计学意义(P＜0.05).红细胞计数、婚姻状况和学历对女性高尿酸血症有影响,对男性影响不大;吸烟、肌酐和舒张压对男性高尿酸血症患者有影响,对女性没有影响.结论 男、女高尿酸血症患者的临床特征及影响因素均有不同,应对不同性别的高尿酸血症患者采取相应的预防和治疗措施.

Investigation on the influencing factors of hyperuricemia in different genders

Objective To compare the clinical characteristics and influence factors of hyperuricemia between genders,in order to provide references for better controlling and preventing the occurrence and development of hyperuricemiaprovide.Methods A total of 5 783 people who underwent physical examination in two Baoding Health Screening Centers from January 1st to June 1st,2016 were enrolled in this study,and all volunteers completed physical examination,laboratory examination and questionnaire survey.Patients with hyperuricemia were selected to analyse the clinical characteristics and influence factors.Results There were statistically significant differences in clinical characteristics,including obesity,blood pressure,blood glucose,blood lipids,liver function,renal function,anemia,blood rheology examination,thyroid ultrasound and lateral radiographs,between male and female patients with hyperuricemia (P＜0.05).The survey showed that there were statistically significant differences in age,education level,marital status,work status,sleeping status,smoking and drinking between male and female patients with hyperuricemia (P＜0.05).The red blood cells counts,marital status and education level were influence factors for female patients with hyperuricemia,while have little effect on male patients.The smoking,creatinine and diastolic blood pressure were influence factors for male patients with hyperuricemia,while have no effect on female patients.Conclusion The clinical characteristics and the influencing factors of male and female patients with hyperuricemia are different,so corresponding preventive and therapeutic measures should be taken for male and female patients.