电子束CT冠状动脉钙化与影像学斑块负荷的量化关系

探讨经电子束CT检测的冠状动脉钙化积分与影像学斑块负荷的量化关系。 32 0例临床疑诊为冠心病而行选择性冠状动脉造影的患者行电子束CT检查 ,并计算冠状动脉钙化积分 ,分析钙化积分与冠状动脉粥样斑块负荷之间的关系。结果发现 ,全组冠状动脉钙化积分为 0～ 3 346 ,中位数 45 ,钙化积分的自然对数转换值平均为 3 .64± 2 .1 8。钙化积分的自然对数转换值与狭窄程度呈轻度正相关 (r=0 .385 ,P <0 .0 0 1 ) ,与斑块负荷总分呈高度正相关 (r=0 .768,P <0 .0 0 1 )。结果提示 ,电子束CT检测的冠状动脉钙化积分与斑块负荷之间有良好的相关性 ,而与狭窄程度的相关性较差。

The Quantitative Correlation between Coronary Calcium Score Detected by Electron Beam Computed Tomography and Angiographically Atherosclerotic Plaque Burden

Aim To investigate the quantitative correlation between coronary calcium score (CS) determined by electron beam computed tomography (EBCT) and angiographically atherosclerotic plaque burden. Methods In 320 patients who were clinically suspected to have coronary artery disease and had undergone coronary angiography, EBCT was performed for calculating calcium score. The relation of calcium score to atherosclerotic plaque burden was quantitatively analyzed. Results The calcium score ranged from 0 to 3 346, with a median of 45. The mean natural logarithm transformation of calcium score ) was 3.64±2.18. LN(CS+1) was poorly related to stenosis severity (r=0.385, p<0.001) and well related to the total score of plaque burden (r=0.768, p<0.001). Conclusion Calcium score determined by electron beam computed tomography correlates intimately with plaque burden but poorly with stenosis severity.