Timing of placental delivery to prevent post-partum haemorrhage: lessons learned from an abandoned randomised clinical trial |
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Authors: | Magann Everett F Doherty Dorota A Briery Christian M Niederhauser Amy Morrison John C |
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Affiliation: | Department of Obstetrics, Naval Medical Center Portsmouth, Portsmouth, Virginia, USA. |
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Abstract: | It has been recognised that, if the length of the third stage of labour exceeds 30 min, then there is an increased risk of a post-partum haemorrhage. Recent information has suggested that 18 min is the optimal time for removal of the undelivered placenta to prevent a post-partum haemorrhage. A randomised trial comparing 20 vs. 30 min was stopped after an interim analysis because only eight of 1607 patients' placentas had not delivered by 20 min. A third stage of labour that exceeded 10 min was observed to be significantly correlated with an increased risk of post-partum haemorrhage. |
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Keywords: | post-partum haemorrhage third stage of labour |
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