国人胚胎顶骨组织结构的胎龄性变化

目的　完善国人胚胎颅顶骨发生及发育的形态学资料。方法　取第 9～ 38周人胚胎 32例的颅顶骨 ,用HE、硫堇 苦味酸法染色 ,光镜观察。结果　第 9周胚胎顶骨为一片间充质膜。第 10～ 12周胚胎的膜性顶骨内 ,血管丰富 ,有针片状骨小梁形成 ;第 13～ 16周胚胎顶骨内骨小梁增加 ,呈条索状。第 17周以后 ,顶骨内的骨小梁增粗增长 ,连接成骨小梁网 ,并有原始哈氏系统形成 ;第 2 9周以后 ,顶骨内的原始哈氏系统不断增加 ,原始密质骨逐渐形成。结论　人胚胎颅顶骨发育过程中有原始哈氏系统形成 ,胚胎颅骨的发育及结构特点与胚胎脑的不断生长 ,使其承受的重量不断增加有关

Age-related changes in histological structure of the parietal bone of Chinese fetus

Objective To perfect morphological data about genesis and development of cranial bones of Chinese fetus.Methods The sections of parietal bones of human fetuses ranging in gestational age from 9th to 38 weeks were stained with Hematoxylin Eosin and thionin Trinitrophenol methods,and then observed with light microscopy.Results The parietal bones of the 9th week fetuses were a laver of mesenchyme membrane.The rich blood vessels were present and the spiculate bony trabuculae were forming in the membranous parietal bones of 10th to 12 weeks fetuses.The bony trabeculae were increasing and in the from of a irregular bar or cord in the parietal bones of 13th to 16 weeks fetuses.After 17th week,the bone trabeculae in parietal bones became thicker and longer and connected with one another to form a network of trabeculae in which the primitive Haversian systems were built.After 29th week,the primitive Haversian systems constantly increased and the primitive compact bone gradually formed in parietal bones.Conclusion There were the primitive Haversian systems forming during the development of cranial bone of human fetuses.The development and structure of human fetal skull related to the fetal brain constantly growing that caused it to support continuously increased weight.