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Use of Transrenal DNA for the Diagnosis of Extrapulmonary Tuberculosis in Children: a Case of Tubercular Otitis Media
Authors:Roberta Petrucci  Giulia Lombardi  Ilaria Corsini  Francesca Visciotti  Antonio Pirodda  Salvatore Cazzato  Maria Paola Landini  Paola Dal Monte
Affiliation:aPaediatric Unit, S. Orsola-Malpighi University Hospital, Bologna, Italy;bMicrobiology Unit, Department of Experimental, Diagnostic and Specialty Medicine, S. Orsola-Malpighi University Hospital, Bologna, Italy;cAudiology and Otology Unit, Department of Experimental, Diagnostic and Specialty Medicine, S. Orsola-Malpighi University Hospital, Bologna, Italy
Abstract:The diagnosis of tuberculosis (TB) is difficult in children, especially for smear-negative pulmonary and extrapulmonary TB, which are common at this age. We report an 11-year-old girl with TB otitis media with negative smear microscopy and Xpert MTB/RIF but positive Mycobacterium tuberculosis-specific transrenal DNA (Tr-MTB-DNA) test results and culture for M. tuberculosis.
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