甲型和乙型流感确诊患者血浆C反应蛋白和血常规结果分析

目的 探讨甲型和乙型流感确诊病例C反应蛋白（CRP）、WBC、中性粒细胞和中性粒细胞比率的变化及意义.方法 将534例发热门诊患者分为3组,甲型流感组207例、乙型流感组89例,238例.分别检测CRP和白细胞计数等指标并进行比较.结果 甲型流感组和乙型流感组WBC[（7.1±2.1）＆#215;109/L、（7.2±1.8）＆#215;109/L]、中性粒细胞计数[（5.2±1.9）＆#215;109/L、（5.3±1.5）＆#215;109/L]、中性粒细胞的比例（0.73±0.10、0.73±0.09）和CRP[（ 15±8） mg/L、（ 19±11） mg/L]均低于非流感组[分别为（8.8±3.9）G/L、（0.77±0.10）、（41±32） mg/L],差异均有统计学意义（均P〈0.05或P〈0.01）;甲型流感组与乙型流感组之间差异无统计学意义（P〉0.05）.甲型流感组和乙型流感组的体温水平与非流感组比较,差异无统计学意义（P〉0.05）.甲型流感组和乙型流感组各项指标比较,差异无统计学意义（P〉0.05）.3组在白细胞〉10＆#215;109/L 、中性粒细胞计数〉6.4＆#215;109/L 、中性粒细胞比〉0.75 、CRP〉10 mg/L各项中的构成比差异有统计学意义 [甲型流感组：10.6%（22/207）,22.7%（47/207）,45.4%（94/207）,9.7%（20/207）;乙型流感组：3.4%（3/89）,21.3%（19/89）,42.7%（38/89）,18.0%（16/89）;非流感组：23.1%（55/238）,45.8%（109/238）,61.3%（146/238）,34.5%（82/238）,均P〈0.05].结论 检测流感患者CRP和WBC的变化,对判断病情及指导临床用药均有一定的意义.

Analysis of C-reactive protein and blood routine parameters level in patients with influenza A and influenza B

Objective To investigate the changes of C-reactive protein（CRP）, white blood cells count（WBC）,neutrophil（NE）, the percentage of neutrophils （ NE%） level in patients with influenza A and influenza B.Methods Five hundred and thirty four patients were divided into 3 groups as influenza A group（n=207）、influenza B group（n=89） and non-influenza group（n=238）. C-reactive protein and white blood cells count were examined for all subjects. Results In influenza A group, the WBC and NE level were lower than those of non-influenza group （P〈0.01） ; the NE% and CRP level was lower than those of non-influenza group （P〈0.05） [NE%：（73±10）% vs （77±10）%,CRP：（ 15±8） mg/L vs （41±32） mg/L]. In influenza B group, the WBC, NE, NE% and CRP level was lower than those of non-influenza group （P〈0.05） . In influenza A group and influenza B group, the temperature level was changed than those of non-influenza group （P〉0.05）. In influenza A group, the WBC, NE, NE% and CRP level was changed than those of influenza B group（P〉0.05）. There were significant differences in the constituent ratios in three groups [influenza A group：10.6%（22/207）, 22.7%（47/207）, 45.4%（94/207）, 9.7%（20/207）; influenza B group：3.4%（3/89）, 21.3%（19/89）,42.7%（38/89）, 18.0%（16/89）; non-influenza group： 23.1%（55/238）, 45.8%（109/238）, 61.3%（146/238）, 34.5%（82/238）, P〈0.05]. Conclusion Monitoring of C-reactive protein, white blood cells count level is helpful in diagnosis and the instruction clinical medication in patients with influenza.