Zygomycosis over‐infection during voriconazole therapy for aspergillosis in a heart transplant patient,successfully treated with liposomal amphotericin and posaconazole |
| |
| Authors: | P Bourke P Castro R Rabagliati C Beltran H Verdejo JL Winter RC Bourge |
| |
| Institution: | 1. Division de Enfermedades Cardiovasculares, Escuela de Medicina, Facultad de Medicina Pontificia Universidad Católica de Chile, , Santiago, Chile;2. Departamento de Medicina Interna, Escuela de Medicina, Facultad de Medicina Pontificia Universidad Católica de Chile, , Santiago, Chile;3. Departamento de Otorrinolaringología, Escuela de Medicina, Facultad de Medicina Pontificia Universidad Católica de Chile, , Santiago, Chile;4. Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, , Birmingham, Alabama, USA |
| |
| Abstract: | Aspergillosis and zygomycosis are life‐threatening fungal infections in immunocompromised patients. We report a heart transplant recipient with an early pulmonary invasive aspergillosis successfully treated with association of voriconazole and caspofungin. Zygomycosis sinusitis, which was diagnosed while he still was on voriconazole therapy, was successfully treated with the use of combination antifungal therapy including liposomal amphotericin plus posaconazole and conservative surgical debridement. |
| |
| Keywords: | zygomycosis heart transplant |
|
|
