18氟脱氧葡萄糖-正电子发射体层显像在贲门癌定性诊断中的价值

目的　探讨18氟脱氧葡萄糖 (FDG) 正电子发射体层显像 (PET)检查在贲门癌定性诊断中的价值。方法　对 1998年 12月至 2 0 0 2年 4月我院收治的 2 7例全身FDG PET检查时贲门部有异常FDG高摄取区域患者的临床资料进行回顾性分析 ,PET结果采用目测法与半定量分析方法进行判断 ,同病理诊断以及随访结果对照。结果　 16例贲门癌患者显影与 11例非特异性显影均被目测法判断为恶性肿瘤 ;半定量分析中 16例贲门癌的最大与平均标准摄取值 (SUVmax与SUVmean)分别为 6 71± 2 75与 5 4 6± 2 31,11例胃底贲门非特异性显影的SUVmax与SUVmean分别为2 99± 0 6 7与 2 38± 0 5 1,贲门癌高于胃底贲门非特异性显影 (Z =- 4 171,Z =- 4 195 ,P均 <0 0 1)。结论　FDG PET检查目测法对于贲门癌肿瘤的定性价值有限 ,半定量分析方法区分良恶性的阈值有待于病例数的积累

Fluorodeoxyglucose-positron emission tomography in carcinoma of the esophagogastric junction

OBJECTIVE: To assess the value of fluorine-18 fluorodeoxyglucose (FDG)-positron emission tomography (PET) in carcinoma of the esophagogastric junction. METHODS: From December 1998 to April 2002, 27 patients were imaged with FDG-PET and FDG avid masses in the esophagogastric junction were found in every patient. FDG-PET data was analyzed by visual method and standardized uptake value (SUV). FDG-PET results were compared with pathological results and follow-up survey. RESULTS: 16 carcinomas of the esophagogastric junction and 11 non-specific FDG-avid masses of normal stomach were all considered malignant by visual method. Maximum and mean Standard uptake value (SUV) of cancer were 6.71 +/- 2.75 and 5.46 +/- 2.31, respectively; SUVmax and SUVmean of non-specific FDG avid mass were 2.99 +/- 0.67 and 2.38 +/- 0.51 respectively; SUV of cancer was higher than that of non-specific FDG avid mass (Z = -4.171, Z = -4.195, P < 0.01). CONCLUSIONS: FDG-PET has limited value in differentiating carcinoma of the esophagogastric junction from non-specific FDG avid mass of normal stomach.