| 成骨细胞分化与信号转导研究进展 |
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| 引用本文： | 赵红斌 张西正 郭勇. 成骨细胞分化与信号转导研究进展[J]. 国外医学:生物医学工程分册, 2005, 28(6): 344-347 |
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| 作者姓名： | 赵红斌 张西正 郭勇 |
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| 作者单位： | 军事医学科学院卫生装备研究所,天津300161 |
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| 基金项目： | 军事医学科学院创新基金资助项目（CX20040703） |
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| 摘 要： | 成骨细胞在骨的生长、发育及形成过程中起重要作用，其分化受严格调控，通过多种信号途径实现对成骨细胞的定向分化。综述了G蛋白信号调节因子、BMP／Smads、MAPK、PI3-k以及细胞因子等信号通路在成骨细胞定向分化方面的研究进展。
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| 关 键 词： | 成骨细胞 分化 信号转导 |
| 收稿时间： | 2005-04-26 |
Progress in reseach of osteoblast differentiation and signal transduction |
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| ZHAO Hong-bin, ZHANG Xi-zheng, GUO Yong. Progress in reseach of osteoblast differentiation and signal transduction[J]. Foreign Medical Sciences(Biomedical Engineering Fascicle), 2005, 28(6): 344-347 |
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| Authors: | ZHAO Hong-bin ZHANG Xi-zheng GUO Yong |
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| Affiliation: | Institute of Medical Equipment, Academy of Military Medical Science, Tianjin 300161, China |
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| Abstract: | Osteoblast plays an important role in bone growth, development, and formation. Osteoblast differentiation is controlled by a varity of signals pathways including G protein, BMP/Smads, MAPK, PI3-k pathways and many cytokines. Recently progress on how these signal transduction pathway regulate osteoblast differentiation is reviewed in this paper. |
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| Keywords: | osteoblast differentiation signal transduction |
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