Broadband miniature optical ultrasound probe for high resolution vascular tissue imaging |
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Authors: | Richard J Colchester Edward Z Zhang Charles A Mosse Paul C Beard Ioannis Papakonstantinou Adrien E Desjardins |
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Institution: | 1.Department of Medical Physics and Biomedical Engineering, University College London, Gower Street, London, WC1E 6BT, UK;2.Department of Electronic and Electrical Engineering, University College London, Gower Street, London, WC1E 6BT, UK |
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Abstract: | An all-optical ultrasound probe for vascular tissue imaging was developed. Ultrasound was generated by pulsed laser illumination of a functionalized carbon nanotube composite coating on the end face of an optical fiber. Ultrasound was detected with a Fabry-Pérot (FP) cavity on the end face of an adjacent optical fiber. The probe diameter was < 0.84 mm and had an ultrasound bandwidth of ~20 MHz. The probe was translated across the tissue sample to create a virtual linear array of ultrasound transmit/receive elements. At a depth of 3.5 mm, the axial resolution was 64 µm and the lateral resolution was 88 µm, as measured with a carbon fiber target. Vascular tissues from swine were imaged ex vivo and good correspondence to histology was observed.OCIS codes: (110.5125) Photoacoustics, (110.2350) Fiber optics imaging, (060.2380) Fiber optics sources and detectors, (170.7170) Ultrasound, (170.0110) Imaging systems |
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