非小细胞肺癌患者术前EBUS-TBNA淋巴结分期与术后病理分期一致性探讨

目的:探索术前超声引导下支气管镜针吸活检术(EBUS-TBNA)淋巴结活检结果与术后病理结果的一致性。方法:回顾性纳入本院2013年1月至2017年12月期间符合纳入标准的、不符合排除标准的非小细胞肺癌患者。以术后病理为金标准，分析术前EBUS-TBNA淋巴结活检的敏感性和特异性等。结果:研究纳入了80例符合纳入标准、不符合排除标准的患者，平均年龄61.1岁，男性占73.8%，病理类型包括腺癌、鳞癌、腺鳞癌等。EBUS-TBNA未见明显并发症，对于全部103枚EBUS-TBNA活检淋巴结，EBUS-TBNA检测的敏感性为96.15%、特异性为100.00%、阳性预测值为100.00%、阴性预测值为89.29%。结论:EBUS-TBNA纵隔淋巴结活检是安全的，对于转移淋巴结判断的敏感性、特异性、阳性预测值、阴性预测值均较高。

Correlation of preoperative lymph node staging by EBUS-TBNA and postoperative pathological staging in non-small cell lung cancer patients

Objective:To investigate the lymph node staging consistence of preoperative EBUS-TBNA biopsy and postoperative pathologic diagnosis.Methods:Non-small cell lung cancer（NSCLC) patients in accordence with the inclusion criteria and inconsistent with the exclusion criteria were retrospectively included from January 2013 to December 2017.Taken postoperative pathologic diagnosis as gold standard，sensitivity and specialty of preoperative EBUS-TBNA lymph node biopsy were calculated and analyzed.Results:80 NSCLC patients receiving operation treatment were included with a histological type of adenocarcinoma，squamous carcinoma and adenosquamous carcinoma and so on.No complication was found to be associated with EBUS-TBNA.The mean age was 61.1 years old and male patients count for 73.8%.Taking all the 103 lymph nodes biopsied by EBUS-TBNA，it could get a sensitivity of 96.15%，a speciality 100.00%，positive predictive value of 100.00% and negative predictive value of 89.29%.Conclusion:Preoperative EBUS-TBNA lymph node biopsy is safe and efficient with excellent sensitivity，speciality，positive predictive value and negative predictive value.