硝普钠治疗老年充血性心力衰竭的临床应用

目的观察静脉应用硝普钠治疗老年充血性心力衰竭患者的疗效及安全性。方法对98位老年充血性心力衰竭患者随机分为硝普钠组和硝酸甘油组，均南微量注射泵经静脉泵入，开始剂量分别为6．25μg／min和5μg／min，根据血压及临床表现调整剂量持续静脉泵入。结果硝普钠组总有效率为96％，硝酸甘油组为78．7％，两组比较，硝普钠组明显优于硝酸甘油组（P〈0．01）。结论硝普钠对老年充血性心力：莨竭患者疗效显著，不良反应较少，对常规治疗效果不佳的老年充血性心力衰竭患者，可应用硝普钠治疗。

Clinical Application of Sodium Nitroprusside in the Treatment of Elderly Congestive Heart Failure

Objective To observe effect and safety of applying sodium nitroprusside in treatment of elderly severe congestive heart failure （CHF） through venous transfusion. Method 98 old patients with CHF were randomly assigned to sodium nitroprusside group and nitroglycerine group. Both of two groups were injected into veins by infusion machine. The beginning dosages were 6.25μg min-1 and 5μg.min-1. The subsequent dosage were adjusted according to blood pressure and clinical status and intravenous injection were be continued. Results The total effective rate of sodium nitroprusside group was 96%, and that of the nitroglycerine group was 78.7%. Obviously the results of sodium nitroprusside group are much better than that of nitroglycerine group. P〈0.01. Conclusion Sodium nitroprusside has remarkable curative effects in old patients with CHF and less side effects. It could be used for the old patients with CHF who fail to use conventional treatment.