| 缺糖基转铁蛋白检测在酒精性肝病诊断中的应用价值 |
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| 引用本文： | 肖燕,杨蓓英,杨顺.缺糖基转铁蛋白检测在酒精性肝病诊断中的应用价值[J].苏州大学学报(自然科学版),2008,28(2):266-268. |
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| 作者姓名： | 肖燕 杨蓓英 杨顺 |
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| 作者单位： | [1]苏州大学附属第二医院检验科,江苏苏州215004 [2]苏州市供电局医务所,江苏苏州215004 |
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| 摘 要： | 目的 检测缺糖基转铁蛋白(CDT)在酒精性肝病(ALD)患者血浆中的水平,并评价其在诊断ALD中的作用.方法 采用乳胶颗粒增强的免疫散射比浊法、双波长速率法、血常规分析分别检测ALD患者、非ALD的其他肝病(NALD)患者及正常对照组血浆中CDT、AST、ALT、GGT水平和红细胞平均体积(MCV).结果 NALD组GGT、ALT、AST浓度明显高于正常对照组,差异有统计学意义(P<0.05).ALD组?T、GGT、ALT浓度与正常对照组比较,差异有统计学意义(P<0.05);ALD组MCV、血浆AST浓度与正常对照组比较,差异无统计学意义(P>0.05).ALD组与NALD组比较,?T显著增加,GGT、ALT、AST浓度较低,差异均有统计学意义(均P<0.05);MCV的差异无统计学意义(P>0.05).结论 ?T可作为诊断酒精性肝病较为理想的检测指标.
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| 关 键 词： | 缺糖基转铁蛋白 酒精性肝病 诊断 糖基 蛋白检测 酒精性 肝病诊断 应用 价值 Alcoholic Liver Disease Cases Level Transferrin Plasma Determination 检测指标 比较 统计学意义 差异 浓度 结果 红细胞平均体积 平和 |
| 文章编号： | 1673-0399(2008)02-0266-03 |
| 修稿时间： | 2007年10月7日 |
Applied Value on Determination of the Plasma Carbohydrate-deficient Transferrin Level in Cases of Alcoholic Liver Disease |
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| XIAO Yan,YANG Bei-ying,YANG Shun.Applied Value on Determination of the Plasma Carbohydrate-deficient Transferrin Level in Cases of Alcoholic Liver Disease[J].Suzhou University Journal of Medical Science,2008,28(2):266-268. |
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| Authors: | XIAO Yan YANG Bei-ying YANG Shun |
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| Institution: | XIAO Yan1,YANG Bei-ying2,YANG Shun1 (1.Dept of Laboratory,the Second Hospital Affiliated to Suzhou University,Jiangsu Suzhou 215004,China,2.The Infirmary of Suzhou Power Supply Bureau,China) |
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| Abstract: | Objective To determine the level of plasma carbohydrate deficient transferrin(CDT) and evaluate its application prospect in diagnosis of alcoholic lever disease(ALD). Methods The plasma CDT level was determined by turbidimetric immunoassay; the ALT,AST and GGT level were measured by double wave length speed assay and the MCV was gained from the EX-2000 blood cell analyzer. Results The level of plasma ALT, AST and GGT in cases of NALD were all higher than that in the healthy people(P<0.05).The level of plasm... |
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| Keywords: | carbohydrate-deficient transferrin alcoholic 1iver disease diagnosis |
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