低剂量MSCT筛查早期肺癌在临床中应用的可行性

目的探讨低剂量多层螺旋CT（MSCT）筛查早期肺癌在临床工作中的可行性。方法常年吸烟或患有慢性阻塞性肺疾病的体检者210名，年龄平均48（43—57）岁（单位体检和自行主张要求检查者）。采用Geliqhtspeed ultra（MSCT）扫描机。参数为：螺旋扫描方式，120kV，50mA，螺距1．35：1，27mm／r，重建层厚2．5mm，间隔2．5mm，肺重建算法，扫描时间12～15s，肺窗-600HU，窗宽1500HU。以多平面重建（MPR）电影方式观察，图象存储方式为DVD光盘。检查费用为200元人民币。结果检出非钙化结节32例，2例为1期病变。结论低剂量MSCT筛查早期肺癌，无论在安全剂量上、检出质量上，还是在成本和医者费用上都是可行的。

Feasibility on Clinical Application of Low Dose MSCT in Screening for Early Lung Cancer

Objective]To discuss the feasibility in the clinical of low-dose Multi-slice Spiral CT (MSCT) in screening for early lung cancer.Methods]210 physical examinees (group physical examination or individual request physical examination actively)with perennial smoking habit or chronic obstructive pulmonary disease were observed, which average age was 48 (43～57) years old. GELightSpeed Ultra MSCT was adopted, which with parameters of spiral scan mode, 120kV, 50mA, pitch 1.35 ∶ 1,27 mm/r,reconstruction thickness 2.5 mm,interval 2.5 mm,reconstruction algorithm, scanning time 12～15 s, lung window-600 HU, window width 1500 HU. The film mode of Multi-planar reconstruction (MPR) was adopted to observe, and the images stored in DVD disc. Examination cost was 200 RMB.Results]32 cases of non-calcified nodules were detected, in which 2 cases were in stage I.Conclusion]Low-dose MSCT was feasible in screening for early lung cancer, not only in safe dose and detected-quality, but also in cost and expense.