Functional changes of the neuronal and glial elements at the surface of the external layer of the median eminence |
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Authors: | Werner Wittkowski and Albert Scheuer |
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Institution: | (1) Anatomisches und Physiologisch-Chemisches Institut der Universität Bonn, Bonn, Deutschland |
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Abstract: | Summary The vascular surface of the external layer of the median eminence is composed of neuronal and glial processes. Neuro-vascular contacts are supposed to be necessary for the release of hypophysiotropic neurohormones.The present study confirms the hypothesis that the relative extent of neuro-vascular and glio-vascular contacts varies under different functional conditions of the tubero-hypophysial system. Morphometric analysis shows that in normal rats about 20% of the surface is lined by neuro-vascular contacts. After bilateral adrenalectomy the neuro-vascular contacts are enlarged to 40% whereas application of an extract of stalk-median eminence tissue is followed by a decrease of the neuro-vascular contacts to 15%. The implications of these results are discussed.A grant of the Landesamt für Forschung NRW is gratefully acknowledged. |
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Keywords: | Median eminence Neuro-vascular contacts Rat |
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