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Landau-Kleffner综合征的临床特征(附3例报告)
引用本文:臧暑雨,李作汉,赵薛旭. Landau-Kleffner综合征的临床特征(附3例报告)[J]. 临床神经病学杂志, 2008, 21(5)
作者姓名:臧暑雨  李作汉  赵薛旭
作者单位:南京医科大学附属脑科医院神经科,210029;南京医科大学附属脑科医院神经科,210029;南京医科大学附属脑科医院神经科,210029
摘    要:目的探讨Landau-Kleffner综合征(LKS)的临床特征。方法回顾性分析3例LKS患者的临床资料。结果3例临床表现均有获得性失语、癫发作及精神行为异常;脑电图呈局灶性棘波放电,头颅CT及MRI未见异常。经治疗癫发作控制较好,但失语及精神行为异常恢复较慢。结论LKS是以获得性失语和癫发作为临床特征;脑电图可见异常放电。治疗后可部分恢复。

关 键 词:Landau-Kleffner综合征  临床特征

Clinical feature of Landau-Kleffner syndrome (report of 3 cases)
ZANG Shu-yu,LI Zuo-han,ZHAO Xue-xu. Clinical feature of Landau-Kleffner syndrome (report of 3 cases)[J]. Journal of Clinical Neurology, 2008, 21(5)
Authors:ZANG Shu-yu  LI Zuo-han  ZHAO Xue-xu
Affiliation:ZANG Shu-yu,LI Zuo-han,ZHAO Xue-xu.Department of Neurology,Brain Hospital Affiliated to Nanjing Medical University,Nanjing 210029,China
Abstract:Objective To investigate the clinical characteristics of Landau-Kleffner syndrome.Methods The clinical data of 3 patients with Landau-Kleffner syndrome was analyzed retrospectively.Results The clinical features of 3 cases presented acquired aphasia,epileptic attack and psychical behaviour abnormality.The EEG showed foci spike wave discharge,while the CT and MRI examination were normal.The epileptic attacks were controlled after treatment,but the recovery of aphasia and psychical behaviour abnormality was poor.Conclusions Acquired aphasia and epileptic attack are the clinical characteristics of Landau-Kleffner syndrome.The EEG shows spike wave dischargeis.Partial recovery can be obtained post-treatment.
Keywords:Landau-Kleffner syndrome  clinical characteristics
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