Lower limb motor restlessness in Asperger's disorder, measured using actometry |
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Authors: | Tuisku Katinka Tani Pekka Nieminen-von Wendt Taina von Wendt Lennart Holi Matti Mikael Porkka-Heiskanen Tarja Lauerma Hannu Lindberg Nina Appelberg Björn Wahlbeck Kristian |
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Affiliation: | Department of Psychiatry, Helsinki University Central Hospital (HUCH), PL 320, Helsinki 18, Finland. |
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Abstract: | The movement disturbances and brain imaging findings in Asperger's disorder (AD) suggest a dopaminergic deficit in movement regulation. Movement disorders of different etiologies have been quantified and specified with actometry. We compared 10 AD patients with 10 healthy controls, measuring their rest-activities by actometry. The lower limb motor activity was significantly higher in the AD group. They also displayed a rhythmic, periodic movement pattern similar to akathisia. These findings suggest a hypothesis of idiopathic akathisia and a special sensitivity to adverse effects of neuroleptic drugs. |
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