| 电针内关对偏头痛大鼠血浆中CGRP含量影响的研究 |
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| 引用本文： | 李桂敏,叶德宝.电针内关对偏头痛大鼠血浆中CGRP含量影响的研究[J].浙江中医药大学学报,2007,31(1):46-47. |
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| 作者姓名： | 李桂敏 叶德宝 |
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| 作者单位： | 浙江中医药大学第三临床医学院,杭州,310053 |
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| 摘 要： | 目的]研究电针内关对大鼠血浆中降钙素基因相关肽(CGRP)含量的影响及其作用机制。方法]皮下注射硝酸甘油注射液(GTN),造成大鼠实验性偏头痛模型。电针内关治疗后,采用放射免疫法测定实验组大鼠血浆中CGRP的含量变化。结果]电针内关能明显降低大鼠血中CGRP的含量。结论]皮下注射GTN能使大鼠血中CGRP含量升高,电针内关可使升高的CGRP含量降低,调节血管扩张状态,改善神经源性炎症,从而使偏头痛症状得以缓解。
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| 关 键 词： | 电针 内关 实验性偏头痛 降钙素基因相关肽 放射免疫法 |
| 文章编号： | 1005-5509（2007）01-0046-02 |
| 修稿时间： | 2006-05-12 |
Research on the Effect of Electro——acupuncture of Neiguan on the CGRP Content in Migraine Rats' Plasma |
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| Li Guimin,Ye Debao.Research on the Effect of Electro——acupuncture of Neiguan on the CGRP Content in Migraine Rats'''' Plasma[J].Journal of Zhejiang University of Traditional Chinese Medicine,2007,31(1):46-47. |
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| Authors: | Li Guimin Ye Debao |
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| Institution: | director;Zhejiang Chinese Medical University, Hangzhou( 310053 |
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| Abstract: | Objective] To study the effect of eletro-acupuncture of Neiguan on the CGRP in rats' plasma and its functional mechanism.Method] Inject subcutaneously GTN to make rats migraine model.After electro-acupuncturing Neiguan,take radio-immune method to measure the CGRP content in rats' plasma of experimental group.Result] Electro-acupuncturing Neiguan can reduce rats CGRP content.Conclusion] To inject subcutaneously GTN can raise rats' plasma CGRP content,electro-acupuncturing Neiguan can reduce risen CGRP,regulate vascular extension,improve nerve inflammation,thus relieve migraine symptoms. |
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| Keywords: | electro-acupuncture Neiguan experimental migraine CGRP radio-immune method |
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