国产和进口非洛地平缓释片治疗高血压病的疗效比较 |
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引用本文: | 刘志高,何学兵. 国产和进口非洛地平缓释片治疗高血压病的疗效比较[J]. 中国新药与临床杂志, 2002, 21(6): 356-358 |
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作者姓名: | 刘志高 何学兵 |
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作者单位: | 1. 华中科技大学同济医学院附属梨园医院,心内科,湖北,武汉,430077 2. 华中科技大学同济医学院,老年医学研究所,湖北,武汉,430077 |
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摘 要: | 目的 :比较国产与进口非洛地平缓释片治疗高血压病的疗效。方法 :国产非洛地平组 6 4例(男性 4 0例 ,女性 2 4例 ,年龄 6 7.8a±s1.3a) ,用国产非洛地平缓释片 5~ 10mg ,po ,qd× 8wk治疗 ;进口非洛地平组 6 4例 (男性 38例 ,女性 2 6例 ,年龄6 8.9a± 1.3a)用进口非洛地平缓释片 5~ 10mg ,po ,qd× 8wk治疗。结果 :国产和进口非洛地平缓释片降压总有效率分别为 94 %和 95 % ,2组疗效差别无显著意义 (P >0 .0 5 ) ,不良反应发生率国产组 16 % ,进口组 14% ,差别无显著意义 (P >0 .0 5 )。结论 :国产与进口非洛地平缓释片有相似的降压效果 ,两者使用均安全
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关 键 词: | 非洛地平 高血压 动态血压监测仪 迟效制剂 |
文章编号: | 1007-7669(2002)06-0356-03 |
Domestic felodipine extended release tablets vs imported felodipine extended release tablets in treating hypertension |
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Abstract: | AIM: Domestic felodipine extended release tablets (ER) vs imported felodipine ER in treating hypertension. METHODS: Sixty-four patients (M 40, F 24; age 67.8 a±s1.3 a) received domestic felodipine ER 5-10 mg, po,qd for 8 wk. Another sixty four patients (M 38, F 26;age 68.9 a±1.3 a) received imported felodipine ER 5-10 mg, po, qd for 8 wk. RESULTS: The clinical total effective rate of domestic felodipine ER group was 94 %, without significant difference with that of imported felodipine ER group (95 %) (P>0.05). Adverse reactions of domestic felodipine ER group were the same as those of imported felodipine ER group (16 % vs 14 %, P>0.05). CONCLUSION: Domestic felodipine ER is an effective and safe drug in treating hypertension as well as the imported one. |
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Keywords: | felodipine hypertension ambulatory blood pressure monitoring delayed-action preparations |
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