| 乙型肝炎患者肝组织中前S_2蛋白存在状态的初步研究 |
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| 引用本文： | 于少军,刘逢举,田庚善. 乙型肝炎患者肝组织中前S_2蛋白存在状态的初步研究[J]. 兰州大学学报(医学版), 1991, 0(1) |
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| 作者姓名： | 于少军 刘逢举 田庚善 |
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| 作者单位： | 兰州医学院传染病研究室，兰州医学院传染病研究室，北京医科大学 甘肃省肿瘤医院中西科，教授 |
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| 摘 要： | 为了观察Pre-s_2在肝患者肝组织内的存在状况,本文应用免疫组织化学PAP法对64例乙肝患者肝组织石蜡切片进行了Pre-s_2检测,同时应用PAP法或ABC法检测了HBsAg和HBcAg。结果表明:(1)乙肝肝组织石蜡切片上能检出Pre-s_2,经胰蛋白酶消化则能破坏Pre-s_2;(2)Pre-s_2与HBsAg在肝组织内存在状况基本一致;(3)粗膜型Pre-s_2主要见于病变明显的肝组织中,其分布区易见到肝细胞坏死现象。
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| 关 键 词： | Pre-s_2 PAP法 肝组织 |
A Freliminary Study on Presence of Pre-s_2in Hepatitis B Infected Livers |
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| Yu shaojun,et al. A Freliminary Study on Presence of Pre-s_2in Hepatitis B Infected Livers[J]. Journal of Lanzhou University (Medical Sciences), 1991, 0(1) |
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| Authors: | Yu shaojun et al |
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| Abstract: | Sixty-four liver specimens from patients with HBV infectien were examined forpre-s_2 with immunohistochemical PAP technique. Pre-s_2 was detected in paraffin sections of fiver tissue and could be detroyed by digestion with trypsin.The pattern of pre-s_2 expression and distribution in the fiver was similar to that of HBsAg.In the areas of coarse membranous expression of pre-s_2,which was mainly present in CAH,liver cell necresis were easily observed. |
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| Keywords: | Pre-s_2:Immunlhistochemistry PAP Liver tissue |
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