Elevated Plasma Homocysteine in Alcoholics |
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Authors: | B Hultberg M Berglund A Andersson A Frank |
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Institution: | Department of Clinical Chemistry, University Hospital, Lund, Sweden.;Alcohol Disease, MalmöGeneral Hospital, Malmö, Sweden. |
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Abstract: | A significantly higher concentration of plasma homocysteine compared with controls was noted in a group of alcoholics ( n = 42) hospitalized for detoxication. Normal concentrations of plasma homocysteine were reached within 1 or 2 weeks after admission to the hospital. In another group of abstinent alcoholics ( n = 16) plasma homocysteine did not deviate from that of controls. Since hyperhomocysteinemia has been associated with premature vascular disease, we speculate that the increased plasma homocysteine in alcoholics might cause the increased incidence of stroke found in these patients. |
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Keywords: | Alcoholics dFolates dHomocysteine dPlasma |
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