不同症状群强迫症患者的生活质量比较

目的探讨强迫症患者的症状群对其生活质量的影响。方法收集78例门诊强迫症患者（病例组）及60名正常对照,采用世界卫生组织生存质量测定量表简表（WHOQOL-BREF）中文版调查生活质量。对强迫症患者的耶鲁-布朗强迫症状检查提纲评分进行分析。结果病例组WHOQOL-BREF量表的生理领域、心理领域、社会关系领域、环境领域得分[分别为（64.7±10.3）分、（47.6±11.5）分、（53.1±12.2）分、（63.7±10.6）分]均低于正常对照组[分别为（79.2±9.6）分、（71.2±10.4）分、（74.1±9.8）、（75.1±10.3）分],差异有统计学意义（t值分别为-8.3、-12.5、-10.9、-6.3,P值均〈0.001）。根据患者的主要症状分为洗涤组、检查组、贮物组、对称组。方差分析显示4组患者WHOQOL-BREF各领域得分均存在差异（P〈0.05）。结论强迫症患者生活质量低于正常人群。不同症状群强迫症患者的生活质量受损害的领域存在差异。

Symptom dimensions were related to different impairments of quality of life in patients with obsessive-compulsive disorder

Objective：To investigate the impairments of quality of life in patients with obsessive-compulsive disorder（OCD）,and explore different impairments of quality of life related to symptom dimensions.Methods： The world health organization quality of live（WHOQOL）-BREF was administered to 78 outpatients with OCD and 60 normal controls,and their score were compared.An analysis was performed on the major categories of the Yale-Brown obsessive-compulsive scale（YBOCS） symptom checklist to derive symptom dimension scores.Results：Compared to normal controls,patients with OCD were showed significant impairment in all domains of quality of life（P0.001）.OCD patients with distinct symptom dimensions of washing,checking,hoarding or symmetry showed different severity of the impairments in most domains of quality of life（P0.05）.Conclusion：Quality of life is severely impaired in patients with OCD.The symptom dimensions were related to different impairments of quality of life in patients with OCD.