A 4-year-old girl with autosomal dominant polycystic kidney disease complicated by a ruptured intracranial aneurysm |
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Authors: | Kubo Satomi Nakajima Mitsuru Fukuda Kazuyoshi Nobayashi Misato Sakaki Toshisuke Aoki Katsuya Hirao Yoshihiko Yoshioka Akira |
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Affiliation: | (1) Department of Paediatrics, Nara Medical University, 840 Shijo-cho, 634-8522 Kashihara City, Nara, Japan;(2) Department of Neurosurgery, Nara Medical University, Kashihara City, Nara, Japan;(3) Department of Urology, Nara Medical University, Kashihara City, Nara, Japan |
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Abstract: | In patients with autosomal dominant polycystic kidney disease (ADPKD), intracranial aneurysms (ICAs) are extrarenal manifestations and may result in serious and potentially fatal outcome following rupture. Although ICAs are a well-known complication of ADPKD, nearly all cases of ICA occurring in the context of ADPKD are adults. Here, we report the case of a Japanese girl with ADPKD who developed a subarachnoid haemorrhage (SAH) due to a ruptured ICA at the age of 4 years. Conclusion:This report is intended to raise awareness that the use of noninvasive screening techniques such as three-dimensional CT angiography or magnetic resonance angiography to detect intracranial aneurysms should also be performed in paediatric patients with autosomal dominant polycystic kidney disease. |
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Keywords: | Autosomal dominant polycystic kidney disease Child Intracranial aneurysm Subarachnoid haemorrhage |
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