徐州地区1204例中老年人骨质疏松症流行病学调查

目的 通过测量徐州地区中老年骨密度,分析骨密度的变化规律及骨质疏松症的发病率,为骨质疏松症的防治提供参考依据.方法 采用GE-LUNAR公司生产的双能X线骨密度仪对徐州地区2005-2008年1204例中老年人进行骨密度测定,分别做股骨上端及第2～4腰椎椎体测量,并按5岁为一个年龄组分组.以峰值骨密度减低2.5标准差为诊断骨质疏松症标准,按性别、年龄分组进行统计学分析.结果 徐州地区男、女各部位骨密度逐年降低,女性55岁后骨量下降较男性显著(P＜0.01),骨质疏松发病率女性高于男性.结论 对中老年人应加强普及骨质疏松预防知识,对于55岁女性和65岁男性,同时采取相应干预措施,以减少骨质疏松症的发生.

An epidemiology survey of bone mineral density and osteoporosis in 1204 elderly people in Xuzhou area.

Objective To analyze the changes of bone mineral density (BMD) and the incidence of osteoporosis in elderly people in Xuzhou area by measuring BMD, and provide reference to osteoporosis prevention and control. Methods From 2005 to 2008, BMD were measured in 1204 elderly people by dual energy X-ray absorptiometry (DEXA). The measurement included the neck of femur and L2-4 of lumbar. All subjects were divided into multiple sections with every 5 year interval. Osteoporosis was diagnosed according to the criteria of BMD peak minus 2. 5 SD. BMD values and the incidence of osteoporosis were analyzed among different age and gender groups. Results BMD of different sites decreased year by year in both male and female in Xuzhou area. After 55years of age BMD decreased more in female than in male ( P ＜ 0. 01 ). The incidence of osteoporosis in female was higher than that in male. Conclusions We should reinforce the health education on osteoporosis prevention. Intervention should be conducted in females older than 55 years and males older than 65 years to decrease the occurrence of osteoporosis.